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Претрага радова објављених у периоду (2019-2022):
Radoičić, M.; Ćirić-Marjanović, G.; Miličević, D.; Suljovrujić, E.; Milošević, M.; Jakovljević, J. Kuljanin; Šaponjić, Z.
Fine-tuning of conductive and dielectric properties of polypyrrole/TiO2 nanocomposite-coated polyamide fabric Journal Article
In: Composite Interfaces, 28 (8), pp. 795-808, 2021.
@article{Radoičić2021795,
title = {Fine-tuning of conductive and dielectric properties of polypyrrole/TiO2 nanocomposite-coated polyamide fabric},
author = {M. Radoičić and G. Ćirić-Marjanović and D. Miličević and E. Suljovrujić and M. Milošević and J. Kuljanin Jakovljević and Z. Šaponjić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089447238&doi=10.1080%2f09276440.2020.1805219&partnerID=40&md5=a1076e4c6b30b3e10c0db0837b8ec69a},
doi = {10.1080/09276440.2020.1805219},
year = {2021},
date = {2021-01-01},
journal = {Composite Interfaces},
volume = {28},
number = {8},
pages = {795-808},
abstract = {Structural, conductive and dielectric properties of hybrid Polypyrrole (PPy)-TiO2 nanocomposite-coated polyamide fabric (PA-PPy/TiO2) synthesized by in-situ oxidative polymerization of pyrrole on the surface of polyamide in the presence of colloidal TiO2 NPs (d ~ 4.5 nm) have been studied. Raman spectra confirmed salt form of PPy in both neat PPy and PPy/TiO2-coated PA fabric and indicated its complete coverage. SEM/EDX analysis confirmed presence of TiO2 NPs and changes in granular structure of PPy deposited on the surface of PA fiber depending on the amount of TiO2 NPs. The PA-PPy/TiO2 nanocomposite sample with lowest content of TiO2 NPs (6.79 At.% Ti) showed highest conductivity (~10−6 S/cm) and dissipation factor (tan δ) in the entire frequency range. The lowest amount of TiO2 NPs in the PA-PPy/TiO2 nanocomposite induced two to four orders of magnitude higher tan δ value, compared to neat PPy covered PA fabric, depending on the frequency range. Frequency dependence of real (ϵ′) and imaginary part (ϵ″) of the complex permittivity for neat PA and PPy/TiO2-coated PA fabrics follow the trend of changes in dissipation factor for the same TiO2 NPs concentrations. The presence of TiO2 NPs could be exploited for tuning the conductive and dielectric properties of a conductive layer. © 2020 Informa UK Limited, trading as Taylor & Francis Group.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Stanković, B.
Effect of the swelling degree on the non-isothermal dehydration kinetics of a poly(acrylic acid)-: G -gelatine hydrogel Journal Article
In: Soft Matter, 17 (45), pp. 10383-10393, 2021.
@article{Stanković202110383,
title = {Effect of the swelling degree on the non-isothermal dehydration kinetics of a poly(acrylic acid)-: G -gelatine hydrogel},
author = {B. Stanković},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120432484&doi=10.1039%2fd1sm01139a&partnerID=40&md5=941819cb7db3947d934658c47fdb6fd7},
doi = {10.1039/d1sm01139a},
year = {2021},
date = {2021-01-01},
journal = {Soft Matter},
volume = {17},
number = {45},
pages = {10383-10393},
abstract = {The kinetics of non-isothermal dehydration of a poly(acrylic acid)-g-gelatine hydrogel swollen to different swelling degrees is investigated. The thermogravimetric curves are recorded at different heating rates in the interval from 5 K mol-1 to 20 K mol-1 within the temperature range from ambient temperature to 480 K. It is found that all kinetics curves can be described using the Weibull function. Based on the suggested kinetics model, the values of the specific rates are calculated and the values of apparent activation energies are established. Distribution functions of activation energies are obtained. The changes found in the values of Weibull function parameters, dependences of the specific rate on temperature, and apparent activation energies on temperature and the dehydration degree, as well as different activation energy distributions, are explained using the fluctuation model of a hydrogel, as a dynamically disordered system that goes through changes during the dehydration process. The presented results can have both fundamental and practical significance in the fields where the application is based on the ability of the hydrogel to conserve and slowly release water. © 2021 The Royal Society of Chemistry.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Petrusic, I.; Jovanovic, V.; Kovic, V.; Savic, A.
Characteristics of N400 component elicited in patients who have migraine with aura Journal Article
In: Journal of Headache and Pain, 22 (1), 2021.
@article{Petrusic2021,
title = {Characteristics of N400 component elicited in patients who have migraine with aura},
author = {I. Petrusic and V. Jovanovic and V. Kovic and A. Savic},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121710234&doi=10.1186%2fs10194-021-01375-8&partnerID=40&md5=cdcb51694d2bf027c43910dea1a4b0ce},
doi = {10.1186/s10194-021-01375-8},
year = {2021},
date = {2021-01-01},
journal = {Journal of Headache and Pain},
volume = {22},
number = {1},
abstract = {Background: This study aimed to examine the N400 effect and event-related potentials (ERPs) elicited from congruent and incongruent stimuli in patients who have migraines with aura (MwA). Methods: A total of 33 MwA patients and 20 healthy controls (HCs) were studied. They were balanced in age (35.12 ± 8.94 vs 34.70 ± 9.59 years},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Santos, D. M. F.; Šljukić, B.
Advanced materials for electrochemical energy conversion and storage devices Journal Article
In: Materials, 14 (24), 2021.
@article{Santos2021,
title = {Advanced materials for electrochemical energy conversion and storage devices},
author = {D. M. F. Santos and B. Šljukić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121309146&doi=10.3390%2fma14247711&partnerID=40&md5=fbe315369fb06e0b2b4ec7c192de86e2},
doi = {10.3390/ma14247711},
year = {2021},
date = {2021-01-01},
journal = {Materials},
volume = {14},
number = {24},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Milanović, Ž.; Dimić, D.; Žižić, M.; Milenković, D.; Marković, Z.; Avdović, E.
Mechanism of antiradical activity of newly synthesized 4,7-dihydroxycoumarin derivatives-experimental and kinetic DFT study Journal Article
In: International Journal of Molecular Sciences, 22 (24), 2021.
@article{Milanović2021,
title = {Mechanism of antiradical activity of newly synthesized 4,7-dihydroxycoumarin derivatives-experimental and kinetic DFT study},
author = {Ž. Milanović and D. Dimić and M. Žižić and D. Milenković and Z. Marković and E. Avdović},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120802238&doi=10.3390%2fijms222413273&partnerID=40&md5=7dd8c700ce1f5fd642f51da4ae1c70db},
doi = {10.3390/ijms222413273},
year = {2021},
date = {2021-01-01},
journal = {International Journal of Molecular Sciences},
volume = {22},
number = {24},
abstract = {Coumarin derivatives have proven beneficial biological activities, but the mechanism of their radical scavenging potency is not fully understood. In this study, the antiradical capacity of two newly synthesized 4,7-dihydroxycoumarin derivatives: (E)-3-(1-((3-hydroxy-4-methoxyphenyl)amino)-ethylidene)-2,4-dioxochroman-7-yl acetate (A-3OH) and (E)-3-(1-((4-hydroxy-3-methoxyphenyl) amino)ethylidene)-2,4-dioxochroman-7-yl acetate (A-4OH) towards HO• were examined by Electron Paramagnetic Resonance (EPR) Spectroscopy and Density Functional Theory (DFT). The compounds were fully characterized by the elemental microanalysis, IR, and NMR spectroscopies. The effect of pH on the acid–base equilibria is separately discussed and the predominant species at the physiological pH were determined. Several common mechanisms (Hydrogen Atom Transfer (HAT), Single-Electron Transfer followed by Proton Transfer (SET-PT), Sequential Proton Loss followed by Electron Transfer (SPLET), Radical Adduct Formation (RAF), and Intramolecular Hydrogen Atom Abstraction (iHAA)) of radical scavenging were investigated based on thermodynamic and kinetic parameters. EPR results indicated that both compounds significantly reduce the amount of present HO•. The results of the kinetic DFT study demonstrated that both compounds predominantly exhibit antiradical capacity through HAT and SPLET mechanisms. The estimated overall rate constants (koverall) proved that A-4OH shows better antioxidant capacity than A-3OH which is well-correlated with the results obtained by EPR measurement. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Jovanovic, J. D.; Adnadjevic, B. K.
In: Gels, 7 (4), 2021.
@article{Jovanovic2021,
title = {Kinetics of the release of nicotinamide absorbed on partially neutralized poly(Acrylic-co-methacrylic acid) xerogel under the conditions of simultaneous microwave heating and cooling},
author = {J. D. Jovanovic and B. K. Adnadjevic},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119147562&doi=10.3390%2fgels7040193&partnerID=40&md5=68ce7bb000c448b3b9fb8a95eea5dfe8},
doi = {10.3390/gels7040193},
year = {2021},
date = {2021-01-01},
journal = {Gels},
volume = {7},
number = {4},
abstract = {The kinetics of release of nicotinamide (NIAM) that was absorbed on partially neutralized poly(acrylic-co-methacrylic) (PAM) xerogel/hydrogel, under the conditions of simultaneous microwave heating and cooling (SMHC) were examined. The kinetics curves of NIAM release into an aqueous solution at temperatures of 308–323 K were recorded. By applying the model-fitting method (MFM), it was found that the kinetics of NIAM release can be modeled by a kinetic model of a first-order chemical reaction. The values of the release rate constants (kM ) at different temperatures were calculated, and their values were found to be within the range 8.4 10−3 s−1 −15.7 10−3 s−1 . It has been established that the Arrhenius equation was valid even in the conditions of SMHC. The values of the kinetic parameters (activation energy (Ea) and pre-exponential factor (A) of the NIAM release process adsorbed on PAM xerogel/hydrogel were calculated as follows: Ea = 25.6 kJ/mol and ln (A/s−1 ) = 5.21. It has been proven that the higher value of the rate constant at SMHC in relation to CH is not a consequence of the overheating of the reaction system or the appearance of “hot-points”. The values of change of the enthalpy of activation (∆H*) and the change of entropy of activation (∆S*) were calculated as follows: ∆H* = +23.82 kJ/mol and ∆S* = −201.4 J/mol K. The calculated higher values of the kinetic parameters and thermodynamic parameters of activation are explained by the formation of a specific activated complex under SMHC, whose structure and degree of order are different than in the one formed under CH. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Krunić, M.; Ristić, B.; Bošnjak, M.; Paunović, V.; Tovilović-Kovačević, G.; Zogović, N.; Mirčić, A.; Marković, Z.; Todorović-Marković, B.; Jovanović, S.; Kleut, D.; Mojović, M.; Nakarada, Đ.; Marković, O.; Vuković, I.; Harhaji-Trajković, L.; Trajković, V.
Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death Journal Article
In: Free Radical Biology and Medicine, 177 , pp. 167-180, 2021.
@article{Krunić2021167,
title = {Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death},
author = {M. Krunić and B. Ristić and M. Bošnjak and V. Paunović and G. Tovilović-Kovačević and N. Zogović and A. Mirčić and Z. Marković and B. Todorović-Marković and S. Jovanović and D. Kleut and M. Mojović and Đ. Nakarada and O. Marković and I. Vuković and L. Harhaji-Trajković and V. Trajković},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117824181&doi=10.1016%2fj.freeradbiomed.2021.10.025&partnerID=40&md5=dca6b01a062016c9894c25afee0a0369},
doi = {10.1016/j.freeradbiomed.2021.10.025},
year = {2021},
date = {2021-01-01},
journal = {Free Radical Biology and Medicine},
volume = {177},
pages = {167-180},
abstract = {We investigated the ability of graphene quantum dot (GQD) nanoparticles to protect SH-SY5Y human neuroblastoma cells from oxidative/nitrosative stress induced by iron-nitrosyl complex sodium nitroprusside (SNP). GQD reduced SNP cytotoxicity by preventing mitochondrial depolarization, caspase-2 activation, and subsequent apoptotic death. Although GQD diminished the levels of nitric oxide (NO) in SNP-exposed cells, NO scavengers displayed only a slight protective effect, suggesting that NO quenching was not the main protective mechanism of GQD. GQD also reduced SNP-triggered increase in the intracellular levels of hydroxyl radical (•OH), superoxide anion (O2•−), and lipid peroxidation. Nonselective antioxidants, •OH scavenging, and iron chelators, but not superoxide dismutase, mimicked GQD cytoprotective activity, indicating that GQD protect cells by neutralizing •OH generated in the presence of SNP-released iron. Cellular internalization of GQD was required for optimal protection, since a removal of extracellular GQD by extensive washing only partly diminished their protective effect. Moreover, GQD cooperated with SNP to induce autophagy, as confirmed by the inhibition of autophagy-limiting Akt/PRAS40/mTOR signaling and increase in autophagy gene transcription, protein levels of proautophagic beclin-1 and LC3-II, formation of autophagic vesicles, and degradation of autophagic target p62. The antioxidant activity of GQD was not involved in autophagy induction, as antioxidants N-acetylcysteine and dimethyl sulfoxide failed to stimulate autophagy in SNP-exposed cells. Pharmacological inhibitors of early (wortmannin, 3-methyladenine) or late stages of autophagy (NH4Cl) efficiently reduced the protective effect of GQD. Therefore, the ability of GQD to prevent the in vitro neurotoxicity of SNP depends on both •OH/NO scavenging and induction of cytoprotective autophagy. © 2021},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Lončar, A.; Negrojević, L.; Dimitrić-Marković, J.; Dimić, D.
In: Computational Biology and Chemistry, 95 , 2021.
@article{Lončar2021,
title = {The reactivity of neurotransmitters and their metabolites towards various nitrogen-centered radicals: Experimental, theoretical, and biotoxicity evaluation},
author = {A. Lončar and L. Negrojević and J. Dimitrić-Marković and D. Dimić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115435422&doi=10.1016%2fj.compbiolchem.2021.107573&partnerID=40&md5=b4bc80165fafe90a1762553509f3fe8d},
doi = {10.1016/j.compbiolchem.2021.107573},
year = {2021},
date = {2021-01-01},
journal = {Computational Biology and Chemistry},
volume = {95},
abstract = {In the past few years, there has been a certain interest in nitrogen-centered radicals, biologically important radicals that play a vital role in various processes and constitute many important biological molecules. In this paper, there was an attempt to bridge a gap in the literature that concerns the antiradical potency of monoamine neurotransmitters (dopamine, epinephrine, and norepinephrine) and their metabolites towards these radicals. The most probable radical quenching mechanism was determined for each radical out of three common mechanisms, namely Hydrogen Atom Transfer (HAT), Single Electron Transfer followed by the Proton Transfer (SET-PT), and Sequential Proton Loss Electron Transfer (SPLET). Marcus’ theory was then used to determine the reaction rates for the electron transfer process. SPLET was the most probable mechanism for both reactions with the aminyl and hydrazyl radicals, while HAT and SPLET were plausible mechanisms for reactions with the imidazolyl radical. Special emphasis was put on the investigation of the substituent effect on the preferred mechanism. The necessity of both thermodynamic and kinetic parameters for the comparison of the antiradical potency of compounds was discussed. The same methodology was applied for the theoretical investigation of the reactivity towards DPPH⦁, a member of the hydrazyl radicals. An ecotoxicity analysis was performed to assess the impact the investigated radicals have on the ecosystem. Except for histidine, every other neutral form was either toxic or highly toxic to some of the analyzed marine organisms. © 2021 Elsevier Ltd},
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pubstate = {published},
tppubtype = {article}
}
Janićijević, D.; Jevremović, A.; Ležaić, A. Janošević; Vasiljević, B. Nedić; Uskoković-Marković, S.; Bajuk-Bogdanović, D.; Milojević-Rakić, M.
Comparative assessment of pesticide adsorption capacity and antioxidant activity of Silver Dodecatungstophosphate/HΒEA zeolite composites Journal Article
In: Journal of Environmental Chemical Engineering, 9 (6), 2021.
@article{Janićijević2021,
title = {Comparative assessment of pesticide adsorption capacity and antioxidant activity of Silver Dodecatungstophosphate/HΒEA zeolite composites},
author = {D. Janićijević and A. Jevremović and A. Janošević Ležaić and B. Nedić Vasiljević and S. Uskoković-Marković and D. Bajuk-Bogdanović and M. Milojević-Rakić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115002895&doi=10.1016%2fj.jece.2021.106341&partnerID=40&md5=2518ac8520522058835b0841ab7ab15f},
doi = {10.1016/j.jece.2021.106341},
year = {2021},
date = {2021-01-01},
journal = {Journal of Environmental Chemical Engineering},
volume = {9},
number = {6},
abstract = {Composite materials consisting of the silver salt of dodecatungstophosphoric acid and HBEA zeolite are developed in order to give materials of superior adsorption properties for aqueous pesticide removal. Two-step impregnation and an ion-exchange method with variable constituent mass ratios were employed as synthesis procedures. One of the study goals was to optimize the composite preparation for efficient elimination of glyphosate pesticide and to investigate the modulation of antioxidant activity in the presence of pesticide. Based on comprehensive results, we propose mechanisms for simultaneous glyphosate removal and antioxidant activity. Spectroscopic analysis shows that the applied two-step impregnation method results in advanced composite materials with evenly distributed active sites for glyphosate adsorption and radical-scavenging activity. The original Krishnamurti isotherm is successfully used to fit pesticide adsorption data, pointing to co-operative adsorption of glyphosate on partly saturated adsorbents sites. The amount of glyphosate adsorbed from water suspension was 378 mg per gram of composite material, the highest value reported for glyphosate removal to date. © 2021 Elsevier Ltd},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Marić, S.; Jocić, A.; Krstić, A.; Momčilović, M.; Ignjatović, L.; Dimitrijević, A.
Poloxamer-based aqueous biphasic systems in designing an integrated extraction platform for the valorization of pharmaceutical waste Journal Article
In: Separation and Purification Technology, 275 , 2021.
@article{Marić2021,
title = {Poloxamer-based aqueous biphasic systems in designing an integrated extraction platform for the valorization of pharmaceutical waste},
author = {S. Marić and A. Jocić and A. Krstić and M. Momčilović and L. Ignjatović and A. Dimitrijević},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108062886&doi=10.1016%2fj.seppur.2021.119101&partnerID=40&md5=799d6dfdce0177e9105488993eb75240},
doi = {10.1016/j.seppur.2021.119101},
year = {2021},
date = {2021-01-01},
journal = {Separation and Purification Technology},
volume = {275},
abstract = {Unused/expired pharmaceuticals can be regarded as a source of valuable compounds. Valorization of active pharmaceutical ingredients (APIs) from pharmaceutical waste, as an alternative to widely adopted treatment by incineration, is a big challenge in terms of designing green, efficient, scalable and sustainable separation methods. Concerning these demands, this work aimed to investigate and propose new integrated extraction technology based on aqueous biphasic systems (ABS) with eco-friendly components namely, poloxamer (Pluronic PE 6200) and one of two salts (sodium citrate, cholinium dihydrogenphosphate) or ionic liquid (1-butyl-3-methylimidazolium chloride). Liquid-liquid equilibria of each ABS were determined at room temperature followed by partition experiments in the biphasic medium to evaluate the most favorable systems for APIs extraction (acetaminophen and caffeine from one commercial product, and theophylline from the other). The finely designed ABSs were then employed to separate APIs from pharmaceutical solids and fractionate them. The results show that citrate-based ABS induces the strongest salting-out effect leading to extraction of all APIs to the Pluronic-rich phase with high recovery efficiencies between 79.4 and 97.90%; insoluble compounds were removed as residues while hydrophilic excipients remained in the citrate-rich aqueous phase. Ionic liquid/PL6200-based ABS was further applied to fractionate acetaminophen and caffeine toward opposite phases. These results underpin the viability and adjustability of PL6200-based ABSs within an integrated process, by a deftly selected salting-out agent, as a sustainable and efficient alternative platform with the great potential to be implemented on a larger scale. © 2021 Elsevier B.V.},
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pubstate = {published},
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}
Dimić, D. S.; Milenković, D. A.; Avdović, E. H.; Nakarada, Đ. J.; Marković, J. M. Dimitrić; Marković, Z. S.
Advanced oxidation processes of coumarins by hydroperoxyl radical: An experimental and theoretical study, and ecotoxicology assessment Journal Article
In: Chemical Engineering Journal, 424 , 2021.
@article{Dimić2021,
title = {Advanced oxidation processes of coumarins by hydroperoxyl radical: An experimental and theoretical study, and ecotoxicology assessment},
author = {D. S. Dimić and D. A. Milenković and E. H. Avdović and Đ. J. Nakarada and J. M. Dimitrić Marković and Z. S. Marković},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107044513&doi=10.1016%2fj.cej.2021.130331&partnerID=40&md5=283a47d9ba97fbf91fc81ba21a777ea6},
doi = {10.1016/j.cej.2021.130331},
year = {2021},
date = {2021-01-01},
journal = {Chemical Engineering Journal},
volume = {424},
abstract = {Coumarin derivatives are an example of stable molecules with very complex biodegradation routes in wastewaters. The use of advanced oxidation processes offers a way to their chemical modification to less toxic products. In this study, the experimental reactivity of 4-hydroxycoumarin (1) and its two derivatives towards hydroperoxyl radical (HOO•) was proven by the ESR spectroscopy. The absence of measurable concentration of carbon- and oxygen-centered radicals, except for DEPMPO-HOO• adduct, showed that stable products were formed in the reaction. Two novel mechanisms, namely hydrogen atom abstraction - radical–radical coupling (HAT-RRC) and radical adduct formation-hydrogen atom abstraction (RAF-HAA) were suggested as possible reaction routes between HOO• and coumarin derivatives. Thermodynamic and kinetic parameters were investigated in detail to explain the plausibility of these two mechanisms with special emphasis on the determination of the most active positions. The theoretical calculations were accompanied by the Natural Bond Orbital Theory and Quantum Theory of Atoms in Molecules. The thermodynamically preferred mechanism of the reaction was RAF-HAA, while the highest reaction rate was obtained for the position C3 of 1. The preferred mechanism was further verified by the UV–Vis spectrophotometry and excited state optimization. The examined routes lead to the formation of stable products with lower toxicity towards aquatic organisms, as shown by the eco-toxicology assessment. © 2021},
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pubstate = {published},
tppubtype = {article}
}
Maćešić, S.; Tóth, Á.; Horváth, D.
Origins of oscillatory dynamics in the model of reactive oxygen species in the rhizosphere Journal Article
In: Journal of Chemical Physics, 155 (17), 2021.
@article{Maćešić2021,
title = {Origins of oscillatory dynamics in the model of reactive oxygen species in the rhizosphere},
author = {S. Maćešić and Á. Tóth and D. Horváth},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118771330&doi=10.1063%2f5.0062139&partnerID=40&md5=8c9fa80df30bc82ebc998c334bfd9db6},
doi = {10.1063/5.0062139},
year = {2021},
date = {2021-01-01},
journal = {Journal of Chemical Physics},
volume = {155},
number = {17},
abstract = {Oscillatory processes are essential for normal functioning and survival of biological systems, and reactive oxygen species have a prominent role in many of them. A mechanism representing the dynamics of these species in the rhizosphere is analyzed using stoichiometric network analysis with the aim to determine its capabilities to simulate various dynamical states, including oscillations. A detailed analysis has shown that unstable steady states result from four destabilizing feedback cycles, among which the cycle involving hydroquinone, an electron acceptor, and its semi-reduced form is the dominant one responsible for the existence of saddle-node and Andronov-Hopf bifurcations. This requires a higher steady-state concentration for the reduced electron acceptor compared to that of the remaining species, where the level of oxygen steady-state concentration determines whether the Andronov-Hopf or saddle-node bifurcation will occur. © 2021 Author(s).},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Milovanović, B.; Petković, M.; Popov, I.; Etinski, M.
Water-mediated interactions enhance alkaline earth cation chelation in neighboring cavities of a cytosine quartet in the DNA quadruplex Journal Article
In: Journal of Physical Chemistry B, 125 (43), pp. 11996-12005, 2021.
@article{Milovanović202111996,
title = {Water-mediated interactions enhance alkaline earth cation chelation in neighboring cavities of a cytosine quartet in the DNA quadruplex},
author = {B. Milovanović and M. Petković and I. Popov and M. Etinski},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118950672&doi=10.1021%2facs.jpcb.1c05598&partnerID=40&md5=a86749268d27f6f88038a4f32aafb35c},
doi = {10.1021/acs.jpcb.1c05598},
year = {2021},
date = {2021-01-01},
journal = {Journal of Physical Chemistry B},
volume = {125},
number = {43},
pages = {11996-12005},
abstract = {Larger Coulombic repulsion between divalent cations compared to the monovalent counterparts dictates the cation-cation distance in the central ion channel of quadruplexes. In this work, density functional theory and a continuum solvation model were employed to study bond energies of alkaline earth cations in adjacent cavities of the central ion channel. Four crystallized tetramolecular quadruplexes with various geometric constraints and structural motifs available in the Protein Data Bank were examined in order to understand how the cation binding affinities could be increased in aqueous solution. A cytosine quartet sandwiched between guanine quartets has a larger bond energy of the second alkaline earth cation in comparison with guanine and uracil quartets. Four highly conserved hydrogen-bonded water molecules in the center of the cytosine quartet are responsible for a higher electrostatic interaction with the cations in comparison with guanines' carbonyl groups. The reported findings are valuable for the design of synthetic quadruplexes templated with divalent cations for optoelectronic applications. © 2021 American Chemical Society},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Benazzouz, M. M. Petković; Rakić, A. A.; Trišović, N. P.; Zarić, B. L.; Janjić, G. V.
Supramolecular Perspective of Coordination Effects on Fluorine Interactions Journal Article
In: Crystal Growth and Design, 21 (11), pp. 6129-6142, 2021.
@article{PetkovićBenazzouz20216129,
title = {Supramolecular Perspective of Coordination Effects on Fluorine Interactions},
author = {M. M. Petković Benazzouz and A. A. Rakić and N. P. Trišović and B. L. Zarić and G. V. Janjić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117466245&doi=10.1021%2facs.cgd.1c00584&partnerID=40&md5=a66f6118358b30b500725e074df71920},
doi = {10.1021/acs.cgd.1c00584},
year = {2021},
date = {2021-01-01},
journal = {Crystal Growth and Design},
volume = {21},
number = {11},
pages = {6129-6142},
abstract = {Coordination effects have been considered through the most common interactions in the crystal structures of fluoro compounds (C-H/F and F/F interactions). The supramolecular profile of these effects is based on quantum-chemical calculations for the assessment of the interaction strength and electrostatic potential maps, which provide a qualitative insight into the examined effect. Coordination of aliphatic fluorides leads to an increase of the negative potential of the F atoms, and, hence, an increase in the hydrogen-bonding acceptor ability (strengthening of C-H/F interactions) and a weakening of the F/F interactions, due to an increase in repulsive interactions between the F atoms. There is no significant change in the potential of the F atoms due to coordination of C6-aromatic fluorides, as in the case of aliphatic ones. This results in slight changes in the strengths of the C-H/F and F/F interactions (coupled with parallel interaction at large offsets, PILO), in a noticeable enhancement of stacking interactions, as well as in a significant enhancement of interactions involving the π-system (F/πand C-H/πinteractions). It has also been shown that a decrease in the charge of the metal ions leads to a decrease in the negative potential of the F atom and also that the nature of the metal ion has a significant influence on the value of the potential of the F atoms. ©},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Cvjetinović, Đ.; Milanović, Z.; Mirković, M.; Petrović, J.; Vesković, A.; Popović-Bijelić, A.; Prijović, Ž.; Janković, D.; Vranješ-Đurić, S.
Magnetically induced controlled release from glucose-modified liposomes loaded with Fe3O4 nanoparticles Journal Article
In: Journal of Nanoparticle Research, 23 (11), 2021.
@article{Cvjetinović2021,
title = {Magnetically induced controlled release from glucose-modified liposomes loaded with Fe3O4 nanoparticles},
author = {Đ. Cvjetinović and Z. Milanović and M. Mirković and J. Petrović and A. Vesković and A. Popović-Bijelić and Ž. Prijović and D. Janković and S. Vranješ-Đurić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119824031&doi=10.1007%2fs11051-021-05375-2&partnerID=40&md5=85a0967e64d19fdfdba98821cab741c3},
doi = {10.1007/s11051-021-05375-2},
year = {2021},
date = {2021-01-01},
journal = {Journal of Nanoparticle Research},
volume = {23},
number = {11},
abstract = {Small glucose-modified liposomes (GMLs) were loaded with magnetic Fe3O4 nanoparticles (MNPs) and fluorescein using a standard thin layer preparation procedure and a varying lipid/MNPs ratio. The liposomes were characterized with TEM and DLS measurements, and MNPs encapsulation rate was determined using ICP-OES. Prepared liposomes were stored at 5 °C for 30 days and subsequently exposed to an external magnetic field (20 mT) with varying exposure times (2‒20 min), at room temperature. The release of fluorescein from GMLs induced by the magnetic field exposures was quantified, showing a high release rate (25‒85%) depending on the concentration of MNPs in GMLs. EPR measurements were conducted during the liposomes storage period in order to provide semi-quantitative information of possible MNPs oxidation from Fe3O4 to Fe2O3 inside the liposomes, impacting MNPs magnetic properties. In contrast to the MNPs water dispersion, no significant change in the EPR signal of MNPs encapsulated inside GMLs was detected over the course of 30 days. The data presented in this study indicate that GMLs loaded with MNPs maintain a high stability for prolonged periods of time and that this delivery system may be used for magnetically assisted controlled drug release. Graphical abstract: [Figure not available: see fulltext.] © 2021, The Author(s), under exclusive licence to Springer Nature B.V.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Maksimović, J. Dragišić; Mojović, M.; Vučinić, Ž.; Maksimović, V.
Spatial distribution of apoplastic antioxidative constituents in maize root Journal Article
In: Physiologia Plantarum, 173 (3), pp. 818-828, 2021.
@article{DragišićMaksimović2021818,
title = {Spatial distribution of apoplastic antioxidative constituents in maize root},
author = {J. Dragišić Maksimović and M. Mojović and Ž. Vučinić and V. Maksimović},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108365280&doi=10.1111%2fppl.13476&partnerID=40&md5=25d74508b1a75aa19bf65104d3635b34},
doi = {10.1111/ppl.13476},
year = {2021},
date = {2021-01-01},
journal = {Physiologia Plantarum},
volume = {173},
number = {3},
pages = {818-828},
abstract = {Apoplastic antioxidative constituents (enzymes, primary and secondary metabolites, ROS) from different root zones of hydroponically grown maize (Zea mays L.) were investigated using a noninvasive isolation procedure: filter strip method. Filter strips were placed at specific positions on the root surface: apical zone (tip) and basal zone (base) to absorb apoplastic fluid. Three major classes of low-weight metabolites (organic acids, sugars, and phenolics) have been identified by HPLC-ECD. The longitudinal distribution of sugars and organic acids had the same pattern: higher concentration in the tip than the base, while it was vice versa for phenolics. The specific activities of guaiacol peroxidase, superoxide dismutase, and ascorbate peroxidase were higher in the apoplastic fluid from the root base than the tip, and their different isoforms were separated by isoelectric focusing. Electron paramagnetic resonance (EPR) spectroscopy coupled with the spin-trapping method using DEPMPO showed a persistent generation of hydroxyl radical in the root tip. In vivo EPR imaging of the whole maize root with membrane-permeable and impermeable aminoxyl spin-probes, enabling real-time detection of ROS formation within and outside the membranes, demonstrated ROS accumulation on the root surface, while endodermis and central cylinder were ROS free. For the first time in plant research, 2D EPR images enabled the direct demonstration of site-specific free radical production along the root. Highly sensitive analytical techniques combined with the filter strips, as a non-invasive tool, have increased our knowledge of metabolic processes occurring in the apoplast and their spatial–temporal changes in small regions of the intact root tissue. © 2021 Scandinavian Plant Physiology Society},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Cvjetinović, Đ.; Janković, D.; Milanović, Z.; Mirković, M.; Petrović, J.; Prijović, Ž.; Poghosyan, E.; Vranješ–Đurić, S.
177Lu–labeled micro liposomes as a potential radiosynoviorthesis therapeutic agent Journal Article
In: International Journal of Pharmaceutics, 608 , 2021.
@article{Cvjetinović2021b,
title = {177Lu–labeled micro liposomes as a potential radiosynoviorthesis therapeutic agent},
author = {Đ. Cvjetinović and D. Janković and Z. Milanović and M. Mirković and J. Petrović and Ž. Prijović and E. Poghosyan and S. Vranješ–Đurić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115328927&doi=10.1016%2fj.ijpharm.2021.121106&partnerID=40&md5=b1455630469e9267197ca1c75ce675ff},
doi = {10.1016/j.ijpharm.2021.121106},
year = {2021},
date = {2021-01-01},
journal = {International Journal of Pharmaceutics},
volume = {608},
abstract = {Micro–sized multivesicular liposomes were prepared, radiolabeled with 177Lu, and tested in vitro and in vivo to evaluate the potential of 177Lu–labeled micro liposomes in radiosynoviorthesis (RSO) therapy. A standard reverse–phase procedure of liposome preparation with a lipid mixture of DPPC: CHOL (80:20%) was used for the synthesis. TEM and fluorescence microscopy imaging were performed to determine the size, shape, and structure of the prepared liposomes. Both measurements are in good agreement while TEM micrographs additionally indicate to a large multivesicular inner structure of prepared liposomes. A simple and straightforward procedure was used for liposome radiolabeling with 177Lu, a well–known and commonly used radionuclide in radiotherapy with favorable properties, that can be exploited in RSO therapy. Radiolabeled 177Lu–liposomes were tested in vitro for stability and then injected into the knee joints of Wistar rats where liposome in vivo behavior was followed up to 30 days post injection. Results from both ex vivo biodistribution and in vivo imaging studies presented a high stability and retention (>94 %ID) of 177Lu–micro liposomes in the synovial liquid for the entire observation period. Leakage of free 177Lu or 177Lu–liposomes from the synovial fluid has not been detected, indicating to a possible application of 177Lu–liposomes in radiosynoviorthesis (RSO) therapy. © 2021 Elsevier B.V.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Srećković, N. Z.; Nedić, Z. P.; Liberti, D.; Monti, D. M.; Mihailović, N. R.; Stanković, J. S. Katanić; Dimitrijević, S.; Mihailović, V. B.
In: RSC Advances, 11 (56), pp. 35585-35599, 2021.
@article{Srećković202135585,
title = {Application potential of biogenically synthesized silver nanoparticles using: Lythrum salicaria L. extracts as pharmaceuticals and catalysts for organic pollutant degradation},
author = {N. Z. Srećković and Z. P. Nedić and D. Liberti and D. M. Monti and N. R. Mihailović and J. S. Katanić Stanković and S. Dimitrijević and V. B. Mihailović},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119884274&doi=10.1039%2fd1ra05570d&partnerID=40&md5=220db74010c09889b1d1c8d9aee32a08},
doi = {10.1039/d1ra05570d},
year = {2021},
date = {2021-01-01},
journal = {RSC Advances},
volume = {11},
number = {56},
pages = {35585-35599},
abstract = {This study was designed to evaluate the optimal conditions for the eco-friendly synthesis of silver nanoparticles (AgNPs) using Lythrum salicaria L. (Lythraceae) aqueous extracts and their potential application and safe use. AgNPs synthesized using L. salicaria aerial parts (LSA-AgNPs) and root extract (LSR-AgNPs) were characterized by UV-Vis spectrophotometry, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDS), and X-ray powder diffraction (XRPD). Dynamic light scattering (DLS) was used for the determination of the size distribution profiles of the obtained nanoparticles. Both L. salicaria extracts showed high phenolic content, while the flavone C-glucosides orientin, vitexin, and isovitexin were detected in extracts using HPLC. The synthesized AgNPs displayed growth inhibition of the tested bacteria and fungi in concentrations between 0.156 and 1.25 mg mL-1. The studied nanoparticles also showed antioxidant potential and gained selectivity at different concentrations on different cancer cell lines. Concentrations of LSA-AgNPs were found to be 20.5 and 12 μg mL-1 towards A431 and SVT2, respectively, while LSR-AgNPs were effective only against A431 cancer cells (62 μg mL-1). The hemolytic activity of LSA-AgNPs in concentrations up to 150 μg mL-1 was not observed, while LSR-AgNPs in the highest applied concentration hemolyzed 2.8% of erythrocytes. The degradation possibility of Congo red and 4-nitrophenol using LSA-AgNPs and LSR-AgNPs as catalysts was also proven. The results indicate that L. salicaria may be used for the eco-friendly synthesis of AgNPs with possible applications as antimicrobial and selective cytotoxic agents towards cancer cell lines, as well as in catalytic degradation of pollutants. © The Royal Society of Chemistry.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Milovanovic, B.; Etinski, M.; Popov, I.
Self-assembly of rylene-decorated guanine ribbons on graphene surface for optoelectronic applications: A theoretical study Journal Article
In: Nanotechnology, 32 (43), 2021.
@article{Milovanovic2021,
title = {Self-assembly of rylene-decorated guanine ribbons on graphene surface for optoelectronic applications: A theoretical study},
author = {B. Milovanovic and M. Etinski and I. Popov},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113716082&doi=10.1088%2f1361-6528%2fac162c&partnerID=40&md5=367448a36f8378df5bdd00fb7467fb34},
doi = {10.1088/1361-6528/ac162c},
year = {2021},
date = {2021-01-01},
journal = {Nanotechnology},
volume = {32},
number = {43},
abstract = {We are witnessing a change of paradigm from the conventional top-down to the bottom-up fabrication of nanodevices and particularly optoelectronic devices. A promising example of the bottom-up approach is self-assembling of molecules into layers with predictable and reproducible structural, electronic and optical properties. Nucleobases possess extraordinary ability to self-assembly into one-, two-, and three-dimensional structures. Optical properties of nucleotides are not suitable for wider application to optoelectronics and photovoltaics due to their large optical band gap, which is in contrast to rylene-based dyes that have been intensively investigated in organic optoelectronics. However, these lack the self-assembly capability of nucleobases. Combinations of covalently decorated guanine molecules with rylene type chromophores present 'the best of the both worlds'. Due to the large size of such compounds and its flexible nature their self-assemblies have not been fully understood yet. Here, we use a theoretical approach to study the structural, energetic and optical properties of rylene-based dye decorated guanine (GPDI), as self-assembled on a graphene sheet. Particularly we utilize the density-functional based tight-binding method to study atomic structure of these systems including the potential energy surface of GPDI and stability and organization of single- and multilayered GPDIs on graphene sheet. Using density-functional theory (DFT) we employ the energy decomposition analysis to gain a deeper insight into the contributions of different moieties to stability of GPDI films. Using time dependent DFT we analyze optical properties of these systems. We find that atomically thin films consisting of only a few molecular layers with large surface areas are more favorable than isolated thick islands. Our study of excited states indicates existence of charge separated states similar to ones found in the well-studied hydrogen bonded organic frameworks. The self-assembly characterized with a large homogeneous coverage and long-living charge-separated states provide the great potential for optoelectronic applications. © 2021 IOP Publishing Ltd.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Milovanović, M.
Small lithium-chloride clusters: Superalkalis, superhalogens, supersalts and nanocrystals Journal Article
In: Journal of Computational Chemistry, 42 (26), pp. 1895-1904, 2021.
@article{Milovanović20211895,
title = {Small lithium-chloride clusters: Superalkalis, superhalogens, supersalts and nanocrystals},
author = {M. Milovanović},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111068984&doi=10.1002%2fjcc.26722&partnerID=40&md5=c634f1eeb298fca1469f65f36bda019d},
doi = {10.1002/jcc.26722},
year = {2021},
date = {2021-01-01},
journal = {Journal of Computational Chemistry},
volume = {42},
number = {26},
pages = {1895-1904},
abstract = {In the present paper, the results of the theoretical investigation of the small lithium-chloride clusters are reported. The geometrical structures, electronic and thermodynamic stability of superalkalis, superhalogens, and their single and double charged ions are obtained using efficient and accurate quantum chemistry methods. Further, low-lying isomers of the LinCln ((Formula presented.)) clusters and their stability parameters are calculated. Two ways of formation of the LinCln clusters, polymerization of LiCl fragments and combination of superalkalis and superhalogen clusters, are compared. By examination the lattice energy and the average Li-Cl bond length in rectangular LinCln ((Formula presented.)) clusters, it was concluded that already 50 LiCl are enough to mostly resembles the structure and stability of the bulk LiCl. © 2021 Wiley Periodicals LLC.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2021
Radoičić, M.; Ćirić-Marjanović, G.; Miličević, D.; Suljovrujić, E.; Milošević, M.; Jakovljević, J. Kuljanin; Šaponjić, Z.
Fine-tuning of conductive and dielectric properties of polypyrrole/TiO2 nanocomposite-coated polyamide fabric Journal Article
In: Composite Interfaces, 28 (8), pp. 795-808, 2021.
@article{Radoičić2021795,
title = {Fine-tuning of conductive and dielectric properties of polypyrrole/TiO2 nanocomposite-coated polyamide fabric},
author = {M. Radoičić and G. Ćirić-Marjanović and D. Miličević and E. Suljovrujić and M. Milošević and J. Kuljanin Jakovljević and Z. Šaponjić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089447238&doi=10.1080%2f09276440.2020.1805219&partnerID=40&md5=a1076e4c6b30b3e10c0db0837b8ec69a},
doi = {10.1080/09276440.2020.1805219},
year = {2021},
date = {2021-01-01},
journal = {Composite Interfaces},
volume = {28},
number = {8},
pages = {795-808},
abstract = {Structural, conductive and dielectric properties of hybrid Polypyrrole (PPy)-TiO2 nanocomposite-coated polyamide fabric (PA-PPy/TiO2) synthesized by in-situ oxidative polymerization of pyrrole on the surface of polyamide in the presence of colloidal TiO2 NPs (d ~ 4.5 nm) have been studied. Raman spectra confirmed salt form of PPy in both neat PPy and PPy/TiO2-coated PA fabric and indicated its complete coverage. SEM/EDX analysis confirmed presence of TiO2 NPs and changes in granular structure of PPy deposited on the surface of PA fiber depending on the amount of TiO2 NPs. The PA-PPy/TiO2 nanocomposite sample with lowest content of TiO2 NPs (6.79 At.% Ti) showed highest conductivity (~10−6 S/cm) and dissipation factor (tan δ) in the entire frequency range. The lowest amount of TiO2 NPs in the PA-PPy/TiO2 nanocomposite induced two to four orders of magnitude higher tan δ value, compared to neat PPy covered PA fabric, depending on the frequency range. Frequency dependence of real (ϵ′) and imaginary part (ϵ″) of the complex permittivity for neat PA and PPy/TiO2-coated PA fabrics follow the trend of changes in dissipation factor for the same TiO2 NPs concentrations. The presence of TiO2 NPs could be exploited for tuning the conductive and dielectric properties of a conductive layer. © 2020 Informa UK Limited, trading as Taylor & Francis Group.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Stanković, B.
Effect of the swelling degree on the non-isothermal dehydration kinetics of a poly(acrylic acid)-: G -gelatine hydrogel Journal Article
In: Soft Matter, 17 (45), pp. 10383-10393, 2021.
@article{Stanković202110383,
title = {Effect of the swelling degree on the non-isothermal dehydration kinetics of a poly(acrylic acid)-: G -gelatine hydrogel},
author = {B. Stanković},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120432484&doi=10.1039%2fd1sm01139a&partnerID=40&md5=941819cb7db3947d934658c47fdb6fd7},
doi = {10.1039/d1sm01139a},
year = {2021},
date = {2021-01-01},
journal = {Soft Matter},
volume = {17},
number = {45},
pages = {10383-10393},
abstract = {The kinetics of non-isothermal dehydration of a poly(acrylic acid)-g-gelatine hydrogel swollen to different swelling degrees is investigated. The thermogravimetric curves are recorded at different heating rates in the interval from 5 K mol-1 to 20 K mol-1 within the temperature range from ambient temperature to 480 K. It is found that all kinetics curves can be described using the Weibull function. Based on the suggested kinetics model, the values of the specific rates are calculated and the values of apparent activation energies are established. Distribution functions of activation energies are obtained. The changes found in the values of Weibull function parameters, dependences of the specific rate on temperature, and apparent activation energies on temperature and the dehydration degree, as well as different activation energy distributions, are explained using the fluctuation model of a hydrogel, as a dynamically disordered system that goes through changes during the dehydration process. The presented results can have both fundamental and practical significance in the fields where the application is based on the ability of the hydrogel to conserve and slowly release water. © 2021 The Royal Society of Chemistry.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Petrusic, I.; Jovanovic, V.; Kovic, V.; Savic, A.
Characteristics of N400 component elicited in patients who have migraine with aura Journal Article
In: Journal of Headache and Pain, 22 (1), 2021.
@article{Petrusic2021,
title = {Characteristics of N400 component elicited in patients who have migraine with aura},
author = {I. Petrusic and V. Jovanovic and V. Kovic and A. Savic},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121710234&doi=10.1186%2fs10194-021-01375-8&partnerID=40&md5=cdcb51694d2bf027c43910dea1a4b0ce},
doi = {10.1186/s10194-021-01375-8},
year = {2021},
date = {2021-01-01},
journal = {Journal of Headache and Pain},
volume = {22},
number = {1},
abstract = {Background: This study aimed to examine the N400 effect and event-related potentials (ERPs) elicited from congruent and incongruent stimuli in patients who have migraines with aura (MwA). Methods: A total of 33 MwA patients and 20 healthy controls (HCs) were studied. They were balanced in age (35.12 ± 8.94 vs 34.70 ± 9.59 years},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Santos, D. M. F.; Šljukić, B.
Advanced materials for electrochemical energy conversion and storage devices Journal Article
In: Materials, 14 (24), 2021.
@article{Santos2021,
title = {Advanced materials for electrochemical energy conversion and storage devices},
author = {D. M. F. Santos and B. Šljukić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121309146&doi=10.3390%2fma14247711&partnerID=40&md5=fbe315369fb06e0b2b4ec7c192de86e2},
doi = {10.3390/ma14247711},
year = {2021},
date = {2021-01-01},
journal = {Materials},
volume = {14},
number = {24},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Milanović, Ž.; Dimić, D.; Žižić, M.; Milenković, D.; Marković, Z.; Avdović, E.
Mechanism of antiradical activity of newly synthesized 4,7-dihydroxycoumarin derivatives-experimental and kinetic DFT study Journal Article
In: International Journal of Molecular Sciences, 22 (24), 2021.
@article{Milanović2021,
title = {Mechanism of antiradical activity of newly synthesized 4,7-dihydroxycoumarin derivatives-experimental and kinetic DFT study},
author = {Ž. Milanović and D. Dimić and M. Žižić and D. Milenković and Z. Marković and E. Avdović},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120802238&doi=10.3390%2fijms222413273&partnerID=40&md5=7dd8c700ce1f5fd642f51da4ae1c70db},
doi = {10.3390/ijms222413273},
year = {2021},
date = {2021-01-01},
journal = {International Journal of Molecular Sciences},
volume = {22},
number = {24},
abstract = {Coumarin derivatives have proven beneficial biological activities, but the mechanism of their radical scavenging potency is not fully understood. In this study, the antiradical capacity of two newly synthesized 4,7-dihydroxycoumarin derivatives: (E)-3-(1-((3-hydroxy-4-methoxyphenyl)amino)-ethylidene)-2,4-dioxochroman-7-yl acetate (A-3OH) and (E)-3-(1-((4-hydroxy-3-methoxyphenyl) amino)ethylidene)-2,4-dioxochroman-7-yl acetate (A-4OH) towards HO• were examined by Electron Paramagnetic Resonance (EPR) Spectroscopy and Density Functional Theory (DFT). The compounds were fully characterized by the elemental microanalysis, IR, and NMR spectroscopies. The effect of pH on the acid–base equilibria is separately discussed and the predominant species at the physiological pH were determined. Several common mechanisms (Hydrogen Atom Transfer (HAT), Single-Electron Transfer followed by Proton Transfer (SET-PT), Sequential Proton Loss followed by Electron Transfer (SPLET), Radical Adduct Formation (RAF), and Intramolecular Hydrogen Atom Abstraction (iHAA)) of radical scavenging were investigated based on thermodynamic and kinetic parameters. EPR results indicated that both compounds significantly reduce the amount of present HO•. The results of the kinetic DFT study demonstrated that both compounds predominantly exhibit antiradical capacity through HAT and SPLET mechanisms. The estimated overall rate constants (koverall) proved that A-4OH shows better antioxidant capacity than A-3OH which is well-correlated with the results obtained by EPR measurement. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Jovanovic, J. D.; Adnadjevic, B. K.
In: Gels, 7 (4), 2021.
@article{Jovanovic2021,
title = {Kinetics of the release of nicotinamide absorbed on partially neutralized poly(Acrylic-co-methacrylic acid) xerogel under the conditions of simultaneous microwave heating and cooling},
author = {J. D. Jovanovic and B. K. Adnadjevic},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119147562&doi=10.3390%2fgels7040193&partnerID=40&md5=68ce7bb000c448b3b9fb8a95eea5dfe8},
doi = {10.3390/gels7040193},
year = {2021},
date = {2021-01-01},
journal = {Gels},
volume = {7},
number = {4},
abstract = {The kinetics of release of nicotinamide (NIAM) that was absorbed on partially neutralized poly(acrylic-co-methacrylic) (PAM) xerogel/hydrogel, under the conditions of simultaneous microwave heating and cooling (SMHC) were examined. The kinetics curves of NIAM release into an aqueous solution at temperatures of 308–323 K were recorded. By applying the model-fitting method (MFM), it was found that the kinetics of NIAM release can be modeled by a kinetic model of a first-order chemical reaction. The values of the release rate constants (kM ) at different temperatures were calculated, and their values were found to be within the range 8.4 10−3 s−1 −15.7 10−3 s−1 . It has been established that the Arrhenius equation was valid even in the conditions of SMHC. The values of the kinetic parameters (activation energy (Ea) and pre-exponential factor (A) of the NIAM release process adsorbed on PAM xerogel/hydrogel were calculated as follows: Ea = 25.6 kJ/mol and ln (A/s−1 ) = 5.21. It has been proven that the higher value of the rate constant at SMHC in relation to CH is not a consequence of the overheating of the reaction system or the appearance of “hot-points”. The values of change of the enthalpy of activation (∆H*) and the change of entropy of activation (∆S*) were calculated as follows: ∆H* = +23.82 kJ/mol and ∆S* = −201.4 J/mol K. The calculated higher values of the kinetic parameters and thermodynamic parameters of activation are explained by the formation of a specific activated complex under SMHC, whose structure and degree of order are different than in the one formed under CH. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Krunić, M.; Ristić, B.; Bošnjak, M.; Paunović, V.; Tovilović-Kovačević, G.; Zogović, N.; Mirčić, A.; Marković, Z.; Todorović-Marković, B.; Jovanović, S.; Kleut, D.; Mojović, M.; Nakarada, Đ.; Marković, O.; Vuković, I.; Harhaji-Trajković, L.; Trajković, V.
Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death Journal Article
In: Free Radical Biology and Medicine, 177 , pp. 167-180, 2021.
@article{Krunić2021167,
title = {Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death},
author = {M. Krunić and B. Ristić and M. Bošnjak and V. Paunović and G. Tovilović-Kovačević and N. Zogović and A. Mirčić and Z. Marković and B. Todorović-Marković and S. Jovanović and D. Kleut and M. Mojović and Đ. Nakarada and O. Marković and I. Vuković and L. Harhaji-Trajković and V. Trajković},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117824181&doi=10.1016%2fj.freeradbiomed.2021.10.025&partnerID=40&md5=dca6b01a062016c9894c25afee0a0369},
doi = {10.1016/j.freeradbiomed.2021.10.025},
year = {2021},
date = {2021-01-01},
journal = {Free Radical Biology and Medicine},
volume = {177},
pages = {167-180},
abstract = {We investigated the ability of graphene quantum dot (GQD) nanoparticles to protect SH-SY5Y human neuroblastoma cells from oxidative/nitrosative stress induced by iron-nitrosyl complex sodium nitroprusside (SNP). GQD reduced SNP cytotoxicity by preventing mitochondrial depolarization, caspase-2 activation, and subsequent apoptotic death. Although GQD diminished the levels of nitric oxide (NO) in SNP-exposed cells, NO scavengers displayed only a slight protective effect, suggesting that NO quenching was not the main protective mechanism of GQD. GQD also reduced SNP-triggered increase in the intracellular levels of hydroxyl radical (•OH), superoxide anion (O2•−), and lipid peroxidation. Nonselective antioxidants, •OH scavenging, and iron chelators, but not superoxide dismutase, mimicked GQD cytoprotective activity, indicating that GQD protect cells by neutralizing •OH generated in the presence of SNP-released iron. Cellular internalization of GQD was required for optimal protection, since a removal of extracellular GQD by extensive washing only partly diminished their protective effect. Moreover, GQD cooperated with SNP to induce autophagy, as confirmed by the inhibition of autophagy-limiting Akt/PRAS40/mTOR signaling and increase in autophagy gene transcription, protein levels of proautophagic beclin-1 and LC3-II, formation of autophagic vesicles, and degradation of autophagic target p62. The antioxidant activity of GQD was not involved in autophagy induction, as antioxidants N-acetylcysteine and dimethyl sulfoxide failed to stimulate autophagy in SNP-exposed cells. Pharmacological inhibitors of early (wortmannin, 3-methyladenine) or late stages of autophagy (NH4Cl) efficiently reduced the protective effect of GQD. Therefore, the ability of GQD to prevent the in vitro neurotoxicity of SNP depends on both •OH/NO scavenging and induction of cytoprotective autophagy. © 2021},
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pubstate = {published},
tppubtype = {article}
}
Lončar, A.; Negrojević, L.; Dimitrić-Marković, J.; Dimić, D.
In: Computational Biology and Chemistry, 95 , 2021.
@article{Lončar2021,
title = {The reactivity of neurotransmitters and their metabolites towards various nitrogen-centered radicals: Experimental, theoretical, and biotoxicity evaluation},
author = {A. Lončar and L. Negrojević and J. Dimitrić-Marković and D. Dimić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115435422&doi=10.1016%2fj.compbiolchem.2021.107573&partnerID=40&md5=b4bc80165fafe90a1762553509f3fe8d},
doi = {10.1016/j.compbiolchem.2021.107573},
year = {2021},
date = {2021-01-01},
journal = {Computational Biology and Chemistry},
volume = {95},
abstract = {In the past few years, there has been a certain interest in nitrogen-centered radicals, biologically important radicals that play a vital role in various processes and constitute many important biological molecules. In this paper, there was an attempt to bridge a gap in the literature that concerns the antiradical potency of monoamine neurotransmitters (dopamine, epinephrine, and norepinephrine) and their metabolites towards these radicals. The most probable radical quenching mechanism was determined for each radical out of three common mechanisms, namely Hydrogen Atom Transfer (HAT), Single Electron Transfer followed by the Proton Transfer (SET-PT), and Sequential Proton Loss Electron Transfer (SPLET). Marcus’ theory was then used to determine the reaction rates for the electron transfer process. SPLET was the most probable mechanism for both reactions with the aminyl and hydrazyl radicals, while HAT and SPLET were plausible mechanisms for reactions with the imidazolyl radical. Special emphasis was put on the investigation of the substituent effect on the preferred mechanism. The necessity of both thermodynamic and kinetic parameters for the comparison of the antiradical potency of compounds was discussed. The same methodology was applied for the theoretical investigation of the reactivity towards DPPH⦁, a member of the hydrazyl radicals. An ecotoxicity analysis was performed to assess the impact the investigated radicals have on the ecosystem. Except for histidine, every other neutral form was either toxic or highly toxic to some of the analyzed marine organisms. © 2021 Elsevier Ltd},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Janićijević, D.; Jevremović, A.; Ležaić, A. Janošević; Vasiljević, B. Nedić; Uskoković-Marković, S.; Bajuk-Bogdanović, D.; Milojević-Rakić, M.
Comparative assessment of pesticide adsorption capacity and antioxidant activity of Silver Dodecatungstophosphate/HΒEA zeolite composites Journal Article
In: Journal of Environmental Chemical Engineering, 9 (6), 2021.
@article{Janićijević2021,
title = {Comparative assessment of pesticide adsorption capacity and antioxidant activity of Silver Dodecatungstophosphate/HΒEA zeolite composites},
author = {D. Janićijević and A. Jevremović and A. Janošević Ležaić and B. Nedić Vasiljević and S. Uskoković-Marković and D. Bajuk-Bogdanović and M. Milojević-Rakić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115002895&doi=10.1016%2fj.jece.2021.106341&partnerID=40&md5=2518ac8520522058835b0841ab7ab15f},
doi = {10.1016/j.jece.2021.106341},
year = {2021},
date = {2021-01-01},
journal = {Journal of Environmental Chemical Engineering},
volume = {9},
number = {6},
abstract = {Composite materials consisting of the silver salt of dodecatungstophosphoric acid and HBEA zeolite are developed in order to give materials of superior adsorption properties for aqueous pesticide removal. Two-step impregnation and an ion-exchange method with variable constituent mass ratios were employed as synthesis procedures. One of the study goals was to optimize the composite preparation for efficient elimination of glyphosate pesticide and to investigate the modulation of antioxidant activity in the presence of pesticide. Based on comprehensive results, we propose mechanisms for simultaneous glyphosate removal and antioxidant activity. Spectroscopic analysis shows that the applied two-step impregnation method results in advanced composite materials with evenly distributed active sites for glyphosate adsorption and radical-scavenging activity. The original Krishnamurti isotherm is successfully used to fit pesticide adsorption data, pointing to co-operative adsorption of glyphosate on partly saturated adsorbents sites. The amount of glyphosate adsorbed from water suspension was 378 mg per gram of composite material, the highest value reported for glyphosate removal to date. © 2021 Elsevier Ltd},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Marić, S.; Jocić, A.; Krstić, A.; Momčilović, M.; Ignjatović, L.; Dimitrijević, A.
Poloxamer-based aqueous biphasic systems in designing an integrated extraction platform for the valorization of pharmaceutical waste Journal Article
In: Separation and Purification Technology, 275 , 2021.
@article{Marić2021,
title = {Poloxamer-based aqueous biphasic systems in designing an integrated extraction platform for the valorization of pharmaceutical waste},
author = {S. Marić and A. Jocić and A. Krstić and M. Momčilović and L. Ignjatović and A. Dimitrijević},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108062886&doi=10.1016%2fj.seppur.2021.119101&partnerID=40&md5=799d6dfdce0177e9105488993eb75240},
doi = {10.1016/j.seppur.2021.119101},
year = {2021},
date = {2021-01-01},
journal = {Separation and Purification Technology},
volume = {275},
abstract = {Unused/expired pharmaceuticals can be regarded as a source of valuable compounds. Valorization of active pharmaceutical ingredients (APIs) from pharmaceutical waste, as an alternative to widely adopted treatment by incineration, is a big challenge in terms of designing green, efficient, scalable and sustainable separation methods. Concerning these demands, this work aimed to investigate and propose new integrated extraction technology based on aqueous biphasic systems (ABS) with eco-friendly components namely, poloxamer (Pluronic PE 6200) and one of two salts (sodium citrate, cholinium dihydrogenphosphate) or ionic liquid (1-butyl-3-methylimidazolium chloride). Liquid-liquid equilibria of each ABS were determined at room temperature followed by partition experiments in the biphasic medium to evaluate the most favorable systems for APIs extraction (acetaminophen and caffeine from one commercial product, and theophylline from the other). The finely designed ABSs were then employed to separate APIs from pharmaceutical solids and fractionate them. The results show that citrate-based ABS induces the strongest salting-out effect leading to extraction of all APIs to the Pluronic-rich phase with high recovery efficiencies between 79.4 and 97.90%; insoluble compounds were removed as residues while hydrophilic excipients remained in the citrate-rich aqueous phase. Ionic liquid/PL6200-based ABS was further applied to fractionate acetaminophen and caffeine toward opposite phases. These results underpin the viability and adjustability of PL6200-based ABSs within an integrated process, by a deftly selected salting-out agent, as a sustainable and efficient alternative platform with the great potential to be implemented on a larger scale. © 2021 Elsevier B.V.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Dimić, D. S.; Milenković, D. A.; Avdović, E. H.; Nakarada, Đ. J.; Marković, J. M. Dimitrić; Marković, Z. S.
Advanced oxidation processes of coumarins by hydroperoxyl radical: An experimental and theoretical study, and ecotoxicology assessment Journal Article
In: Chemical Engineering Journal, 424 , 2021.
@article{Dimić2021,
title = {Advanced oxidation processes of coumarins by hydroperoxyl radical: An experimental and theoretical study, and ecotoxicology assessment},
author = {D. S. Dimić and D. A. Milenković and E. H. Avdović and Đ. J. Nakarada and J. M. Dimitrić Marković and Z. S. Marković},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107044513&doi=10.1016%2fj.cej.2021.130331&partnerID=40&md5=283a47d9ba97fbf91fc81ba21a777ea6},
doi = {10.1016/j.cej.2021.130331},
year = {2021},
date = {2021-01-01},
journal = {Chemical Engineering Journal},
volume = {424},
abstract = {Coumarin derivatives are an example of stable molecules with very complex biodegradation routes in wastewaters. The use of advanced oxidation processes offers a way to their chemical modification to less toxic products. In this study, the experimental reactivity of 4-hydroxycoumarin (1) and its two derivatives towards hydroperoxyl radical (HOO•) was proven by the ESR spectroscopy. The absence of measurable concentration of carbon- and oxygen-centered radicals, except for DEPMPO-HOO• adduct, showed that stable products were formed in the reaction. Two novel mechanisms, namely hydrogen atom abstraction - radical–radical coupling (HAT-RRC) and radical adduct formation-hydrogen atom abstraction (RAF-HAA) were suggested as possible reaction routes between HOO• and coumarin derivatives. Thermodynamic and kinetic parameters were investigated in detail to explain the plausibility of these two mechanisms with special emphasis on the determination of the most active positions. The theoretical calculations were accompanied by the Natural Bond Orbital Theory and Quantum Theory of Atoms in Molecules. The thermodynamically preferred mechanism of the reaction was RAF-HAA, while the highest reaction rate was obtained for the position C3 of 1. The preferred mechanism was further verified by the UV–Vis spectrophotometry and excited state optimization. The examined routes lead to the formation of stable products with lower toxicity towards aquatic organisms, as shown by the eco-toxicology assessment. © 2021},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Maćešić, S.; Tóth, Á.; Horváth, D.
Origins of oscillatory dynamics in the model of reactive oxygen species in the rhizosphere Journal Article
In: Journal of Chemical Physics, 155 (17), 2021.
@article{Maćešić2021,
title = {Origins of oscillatory dynamics in the model of reactive oxygen species in the rhizosphere},
author = {S. Maćešić and Á. Tóth and D. Horváth},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118771330&doi=10.1063%2f5.0062139&partnerID=40&md5=8c9fa80df30bc82ebc998c334bfd9db6},
doi = {10.1063/5.0062139},
year = {2021},
date = {2021-01-01},
journal = {Journal of Chemical Physics},
volume = {155},
number = {17},
abstract = {Oscillatory processes are essential for normal functioning and survival of biological systems, and reactive oxygen species have a prominent role in many of them. A mechanism representing the dynamics of these species in the rhizosphere is analyzed using stoichiometric network analysis with the aim to determine its capabilities to simulate various dynamical states, including oscillations. A detailed analysis has shown that unstable steady states result from four destabilizing feedback cycles, among which the cycle involving hydroquinone, an electron acceptor, and its semi-reduced form is the dominant one responsible for the existence of saddle-node and Andronov-Hopf bifurcations. This requires a higher steady-state concentration for the reduced electron acceptor compared to that of the remaining species, where the level of oxygen steady-state concentration determines whether the Andronov-Hopf or saddle-node bifurcation will occur. © 2021 Author(s).},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Milovanović, B.; Petković, M.; Popov, I.; Etinski, M.
Water-mediated interactions enhance alkaline earth cation chelation in neighboring cavities of a cytosine quartet in the DNA quadruplex Journal Article
In: Journal of Physical Chemistry B, 125 (43), pp. 11996-12005, 2021.
@article{Milovanović202111996,
title = {Water-mediated interactions enhance alkaline earth cation chelation in neighboring cavities of a cytosine quartet in the DNA quadruplex},
author = {B. Milovanović and M. Petković and I. Popov and M. Etinski},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118950672&doi=10.1021%2facs.jpcb.1c05598&partnerID=40&md5=a86749268d27f6f88038a4f32aafb35c},
doi = {10.1021/acs.jpcb.1c05598},
year = {2021},
date = {2021-01-01},
journal = {Journal of Physical Chemistry B},
volume = {125},
number = {43},
pages = {11996-12005},
abstract = {Larger Coulombic repulsion between divalent cations compared to the monovalent counterparts dictates the cation-cation distance in the central ion channel of quadruplexes. In this work, density functional theory and a continuum solvation model were employed to study bond energies of alkaline earth cations in adjacent cavities of the central ion channel. Four crystallized tetramolecular quadruplexes with various geometric constraints and structural motifs available in the Protein Data Bank were examined in order to understand how the cation binding affinities could be increased in aqueous solution. A cytosine quartet sandwiched between guanine quartets has a larger bond energy of the second alkaline earth cation in comparison with guanine and uracil quartets. Four highly conserved hydrogen-bonded water molecules in the center of the cytosine quartet are responsible for a higher electrostatic interaction with the cations in comparison with guanines' carbonyl groups. The reported findings are valuable for the design of synthetic quadruplexes templated with divalent cations for optoelectronic applications. © 2021 American Chemical Society},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Benazzouz, M. M. Petković; Rakić, A. A.; Trišović, N. P.; Zarić, B. L.; Janjić, G. V.
Supramolecular Perspective of Coordination Effects on Fluorine Interactions Journal Article
In: Crystal Growth and Design, 21 (11), pp. 6129-6142, 2021.
@article{PetkovićBenazzouz20216129,
title = {Supramolecular Perspective of Coordination Effects on Fluorine Interactions},
author = {M. M. Petković Benazzouz and A. A. Rakić and N. P. Trišović and B. L. Zarić and G. V. Janjić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117466245&doi=10.1021%2facs.cgd.1c00584&partnerID=40&md5=a66f6118358b30b500725e074df71920},
doi = {10.1021/acs.cgd.1c00584},
year = {2021},
date = {2021-01-01},
journal = {Crystal Growth and Design},
volume = {21},
number = {11},
pages = {6129-6142},
abstract = {Coordination effects have been considered through the most common interactions in the crystal structures of fluoro compounds (C-H/F and F/F interactions). The supramolecular profile of these effects is based on quantum-chemical calculations for the assessment of the interaction strength and electrostatic potential maps, which provide a qualitative insight into the examined effect. Coordination of aliphatic fluorides leads to an increase of the negative potential of the F atoms, and, hence, an increase in the hydrogen-bonding acceptor ability (strengthening of C-H/F interactions) and a weakening of the F/F interactions, due to an increase in repulsive interactions between the F atoms. There is no significant change in the potential of the F atoms due to coordination of C6-aromatic fluorides, as in the case of aliphatic ones. This results in slight changes in the strengths of the C-H/F and F/F interactions (coupled with parallel interaction at large offsets, PILO), in a noticeable enhancement of stacking interactions, as well as in a significant enhancement of interactions involving the π-system (F/πand C-H/πinteractions). It has also been shown that a decrease in the charge of the metal ions leads to a decrease in the negative potential of the F atom and also that the nature of the metal ion has a significant influence on the value of the potential of the F atoms. ©},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Cvjetinović, Đ.; Milanović, Z.; Mirković, M.; Petrović, J.; Vesković, A.; Popović-Bijelić, A.; Prijović, Ž.; Janković, D.; Vranješ-Đurić, S.
Magnetically induced controlled release from glucose-modified liposomes loaded with Fe3O4 nanoparticles Journal Article
In: Journal of Nanoparticle Research, 23 (11), 2021.
@article{Cvjetinović2021,
title = {Magnetically induced controlled release from glucose-modified liposomes loaded with Fe3O4 nanoparticles},
author = {Đ. Cvjetinović and Z. Milanović and M. Mirković and J. Petrović and A. Vesković and A. Popović-Bijelić and Ž. Prijović and D. Janković and S. Vranješ-Đurić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119824031&doi=10.1007%2fs11051-021-05375-2&partnerID=40&md5=85a0967e64d19fdfdba98821cab741c3},
doi = {10.1007/s11051-021-05375-2},
year = {2021},
date = {2021-01-01},
journal = {Journal of Nanoparticle Research},
volume = {23},
number = {11},
abstract = {Small glucose-modified liposomes (GMLs) were loaded with magnetic Fe3O4 nanoparticles (MNPs) and fluorescein using a standard thin layer preparation procedure and a varying lipid/MNPs ratio. The liposomes were characterized with TEM and DLS measurements, and MNPs encapsulation rate was determined using ICP-OES. Prepared liposomes were stored at 5 °C for 30 days and subsequently exposed to an external magnetic field (20 mT) with varying exposure times (2‒20 min), at room temperature. The release of fluorescein from GMLs induced by the magnetic field exposures was quantified, showing a high release rate (25‒85%) depending on the concentration of MNPs in GMLs. EPR measurements were conducted during the liposomes storage period in order to provide semi-quantitative information of possible MNPs oxidation from Fe3O4 to Fe2O3 inside the liposomes, impacting MNPs magnetic properties. In contrast to the MNPs water dispersion, no significant change in the EPR signal of MNPs encapsulated inside GMLs was detected over the course of 30 days. The data presented in this study indicate that GMLs loaded with MNPs maintain a high stability for prolonged periods of time and that this delivery system may be used for magnetically assisted controlled drug release. Graphical abstract: [Figure not available: see fulltext.] © 2021, The Author(s), under exclusive licence to Springer Nature B.V.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Maksimović, J. Dragišić; Mojović, M.; Vučinić, Ž.; Maksimović, V.
Spatial distribution of apoplastic antioxidative constituents in maize root Journal Article
In: Physiologia Plantarum, 173 (3), pp. 818-828, 2021.
@article{DragišićMaksimović2021818,
title = {Spatial distribution of apoplastic antioxidative constituents in maize root},
author = {J. Dragišić Maksimović and M. Mojović and Ž. Vučinić and V. Maksimović},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108365280&doi=10.1111%2fppl.13476&partnerID=40&md5=25d74508b1a75aa19bf65104d3635b34},
doi = {10.1111/ppl.13476},
year = {2021},
date = {2021-01-01},
journal = {Physiologia Plantarum},
volume = {173},
number = {3},
pages = {818-828},
abstract = {Apoplastic antioxidative constituents (enzymes, primary and secondary metabolites, ROS) from different root zones of hydroponically grown maize (Zea mays L.) were investigated using a noninvasive isolation procedure: filter strip method. Filter strips were placed at specific positions on the root surface: apical zone (tip) and basal zone (base) to absorb apoplastic fluid. Three major classes of low-weight metabolites (organic acids, sugars, and phenolics) have been identified by HPLC-ECD. The longitudinal distribution of sugars and organic acids had the same pattern: higher concentration in the tip than the base, while it was vice versa for phenolics. The specific activities of guaiacol peroxidase, superoxide dismutase, and ascorbate peroxidase were higher in the apoplastic fluid from the root base than the tip, and their different isoforms were separated by isoelectric focusing. Electron paramagnetic resonance (EPR) spectroscopy coupled with the spin-trapping method using DEPMPO showed a persistent generation of hydroxyl radical in the root tip. In vivo EPR imaging of the whole maize root with membrane-permeable and impermeable aminoxyl spin-probes, enabling real-time detection of ROS formation within and outside the membranes, demonstrated ROS accumulation on the root surface, while endodermis and central cylinder were ROS free. For the first time in plant research, 2D EPR images enabled the direct demonstration of site-specific free radical production along the root. Highly sensitive analytical techniques combined with the filter strips, as a non-invasive tool, have increased our knowledge of metabolic processes occurring in the apoplast and their spatial–temporal changes in small regions of the intact root tissue. © 2021 Scandinavian Plant Physiology Society},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Cvjetinović, Đ.; Janković, D.; Milanović, Z.; Mirković, M.; Petrović, J.; Prijović, Ž.; Poghosyan, E.; Vranješ–Đurić, S.
177Lu–labeled micro liposomes as a potential radiosynoviorthesis therapeutic agent Journal Article
In: International Journal of Pharmaceutics, 608 , 2021.
@article{Cvjetinović2021b,
title = {177Lu–labeled micro liposomes as a potential radiosynoviorthesis therapeutic agent},
author = {Đ. Cvjetinović and D. Janković and Z. Milanović and M. Mirković and J. Petrović and Ž. Prijović and E. Poghosyan and S. Vranješ–Đurić},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115328927&doi=10.1016%2fj.ijpharm.2021.121106&partnerID=40&md5=b1455630469e9267197ca1c75ce675ff},
doi = {10.1016/j.ijpharm.2021.121106},
year = {2021},
date = {2021-01-01},
journal = {International Journal of Pharmaceutics},
volume = {608},
abstract = {Micro–sized multivesicular liposomes were prepared, radiolabeled with 177Lu, and tested in vitro and in vivo to evaluate the potential of 177Lu–labeled micro liposomes in radiosynoviorthesis (RSO) therapy. A standard reverse–phase procedure of liposome preparation with a lipid mixture of DPPC: CHOL (80:20%) was used for the synthesis. TEM and fluorescence microscopy imaging were performed to determine the size, shape, and structure of the prepared liposomes. Both measurements are in good agreement while TEM micrographs additionally indicate to a large multivesicular inner structure of prepared liposomes. A simple and straightforward procedure was used for liposome radiolabeling with 177Lu, a well–known and commonly used radionuclide in radiotherapy with favorable properties, that can be exploited in RSO therapy. Radiolabeled 177Lu–liposomes were tested in vitro for stability and then injected into the knee joints of Wistar rats where liposome in vivo behavior was followed up to 30 days post injection. Results from both ex vivo biodistribution and in vivo imaging studies presented a high stability and retention (>94 %ID) of 177Lu–micro liposomes in the synovial liquid for the entire observation period. Leakage of free 177Lu or 177Lu–liposomes from the synovial fluid has not been detected, indicating to a possible application of 177Lu–liposomes in radiosynoviorthesis (RSO) therapy. © 2021 Elsevier B.V.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Srećković, N. Z.; Nedić, Z. P.; Liberti, D.; Monti, D. M.; Mihailović, N. R.; Stanković, J. S. Katanić; Dimitrijević, S.; Mihailović, V. B.
In: RSC Advances, 11 (56), pp. 35585-35599, 2021.
@article{Srećković202135585,
title = {Application potential of biogenically synthesized silver nanoparticles using: Lythrum salicaria L. extracts as pharmaceuticals and catalysts for organic pollutant degradation},
author = {N. Z. Srećković and Z. P. Nedić and D. Liberti and D. M. Monti and N. R. Mihailović and J. S. Katanić Stanković and S. Dimitrijević and V. B. Mihailović},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119884274&doi=10.1039%2fd1ra05570d&partnerID=40&md5=220db74010c09889b1d1c8d9aee32a08},
doi = {10.1039/d1ra05570d},
year = {2021},
date = {2021-01-01},
journal = {RSC Advances},
volume = {11},
number = {56},
pages = {35585-35599},
abstract = {This study was designed to evaluate the optimal conditions for the eco-friendly synthesis of silver nanoparticles (AgNPs) using Lythrum salicaria L. (Lythraceae) aqueous extracts and their potential application and safe use. AgNPs synthesized using L. salicaria aerial parts (LSA-AgNPs) and root extract (LSR-AgNPs) were characterized by UV-Vis spectrophotometry, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM/EDS), and X-ray powder diffraction (XRPD). Dynamic light scattering (DLS) was used for the determination of the size distribution profiles of the obtained nanoparticles. Both L. salicaria extracts showed high phenolic content, while the flavone C-glucosides orientin, vitexin, and isovitexin were detected in extracts using HPLC. The synthesized AgNPs displayed growth inhibition of the tested bacteria and fungi in concentrations between 0.156 and 1.25 mg mL-1. The studied nanoparticles also showed antioxidant potential and gained selectivity at different concentrations on different cancer cell lines. Concentrations of LSA-AgNPs were found to be 20.5 and 12 μg mL-1 towards A431 and SVT2, respectively, while LSR-AgNPs were effective only against A431 cancer cells (62 μg mL-1). The hemolytic activity of LSA-AgNPs in concentrations up to 150 μg mL-1 was not observed, while LSR-AgNPs in the highest applied concentration hemolyzed 2.8% of erythrocytes. The degradation possibility of Congo red and 4-nitrophenol using LSA-AgNPs and LSR-AgNPs as catalysts was also proven. The results indicate that L. salicaria may be used for the eco-friendly synthesis of AgNPs with possible applications as antimicrobial and selective cytotoxic agents towards cancer cell lines, as well as in catalytic degradation of pollutants. © The Royal Society of Chemistry.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Milovanovic, B.; Etinski, M.; Popov, I.
Self-assembly of rylene-decorated guanine ribbons on graphene surface for optoelectronic applications: A theoretical study Journal Article
In: Nanotechnology, 32 (43), 2021.
@article{Milovanovic2021,
title = {Self-assembly of rylene-decorated guanine ribbons on graphene surface for optoelectronic applications: A theoretical study},
author = {B. Milovanovic and M. Etinski and I. Popov},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113716082&doi=10.1088%2f1361-6528%2fac162c&partnerID=40&md5=367448a36f8378df5bdd00fb7467fb34},
doi = {10.1088/1361-6528/ac162c},
year = {2021},
date = {2021-01-01},
journal = {Nanotechnology},
volume = {32},
number = {43},
abstract = {We are witnessing a change of paradigm from the conventional top-down to the bottom-up fabrication of nanodevices and particularly optoelectronic devices. A promising example of the bottom-up approach is self-assembling of molecules into layers with predictable and reproducible structural, electronic and optical properties. Nucleobases possess extraordinary ability to self-assembly into one-, two-, and three-dimensional structures. Optical properties of nucleotides are not suitable for wider application to optoelectronics and photovoltaics due to their large optical band gap, which is in contrast to rylene-based dyes that have been intensively investigated in organic optoelectronics. However, these lack the self-assembly capability of nucleobases. Combinations of covalently decorated guanine molecules with rylene type chromophores present 'the best of the both worlds'. Due to the large size of such compounds and its flexible nature their self-assemblies have not been fully understood yet. Here, we use a theoretical approach to study the structural, energetic and optical properties of rylene-based dye decorated guanine (GPDI), as self-assembled on a graphene sheet. Particularly we utilize the density-functional based tight-binding method to study atomic structure of these systems including the potential energy surface of GPDI and stability and organization of single- and multilayered GPDIs on graphene sheet. Using density-functional theory (DFT) we employ the energy decomposition analysis to gain a deeper insight into the contributions of different moieties to stability of GPDI films. Using time dependent DFT we analyze optical properties of these systems. We find that atomically thin films consisting of only a few molecular layers with large surface areas are more favorable than isolated thick islands. Our study of excited states indicates existence of charge separated states similar to ones found in the well-studied hydrogen bonded organic frameworks. The self-assembly characterized with a large homogeneous coverage and long-living charge-separated states provide the great potential for optoelectronic applications. © 2021 IOP Publishing Ltd.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Milovanović, M.
Small lithium-chloride clusters: Superalkalis, superhalogens, supersalts and nanocrystals Journal Article
In: Journal of Computational Chemistry, 42 (26), pp. 1895-1904, 2021.
@article{Milovanović20211895,
title = {Small lithium-chloride clusters: Superalkalis, superhalogens, supersalts and nanocrystals},
author = {M. Milovanović},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111068984&doi=10.1002%2fjcc.26722&partnerID=40&md5=c634f1eeb298fca1469f65f36bda019d},
doi = {10.1002/jcc.26722},
year = {2021},
date = {2021-01-01},
journal = {Journal of Computational Chemistry},
volume = {42},
number = {26},
pages = {1895-1904},
abstract = {In the present paper, the results of the theoretical investigation of the small lithium-chloride clusters are reported. The geometrical structures, electronic and thermodynamic stability of superalkalis, superhalogens, and their single and double charged ions are obtained using efficient and accurate quantum chemistry methods. Further, low-lying isomers of the LinCln ((Formula presented.)) clusters and their stability parameters are calculated. Two ways of formation of the LinCln clusters, polymerization of LiCl fragments and combination of superalkalis and superhalogen clusters, are compared. By examination the lattice energy and the average Li-Cl bond length in rectangular LinCln ((Formula presented.)) clusters, it was concluded that already 50 LiCl are enough to mostly resembles the structure and stability of the bulk LiCl. © 2021 Wiley Periodicals LLC.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}